CryoZeta is a de novo macromolecular structure modeling tool that integrates cryo-EM density information with a diffusion-model-based structure prediction pipeline.

It jointly leverages sequence information and cryo-EM map features to generate atomic models consistent with experimental density, and is effective for proteins, protein-nucleic acid complexes, and nucleic acid-only systems at resolutions up to ~8 Å.

If encounter problems, please contact Daisuke Kihara (dkihara@purdue.edu)

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Please simply click "Upload" when you filled all input fields.

Please do not input 0, you must provide a contour to remove the outside very noisy regions

contour_level :


resolution :


cryo_em_map :


fasta(protein) :


fasta(DNA) :


fasta(RNA) :


fit_to_map :
Yes No

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