General & Getting Started

General

Basics of EMSuite Server.

Structure Modeling

CryoZeta

De novo macromolecular structure modeling tool integrating cryo-EM maps and diffusion models.

ComplexModeler

Build full protein-DNA/RNA complex structures from cryo-EM maps using DiffModeler and CryoREAD.

DiffModeler

Build full protein complexes from cryo-EM maps using a diffusion model.

CryoREAD

Build full DNA/RNA atomic structures from cryo-EM maps using deep learning.

DeepMainMast

De novo protein 3D modeling protocol directly from near-atomic resolution cryo-EM maps using deep learning.

MainMast

De novo protein 3D modeling protocol from near-atomic resolution cryo-EM maps.

DMcloud

Macromolecular modeling tool for local structure fitting using point cloud matching with a diffusion model.

DMcloudComplex

Macromolecular structure modeling tool using point cloud matching with diffusion model and 3D U-net (CryoREAD).

Ligand Modeling

Emap2lig

Predict ligand densities in cryo-EM maps and model the ligands into the predicted densities.

Validation & Refinement

DAQ-Refine

Evaluate and refine cryo-EM protein models using DAQ-Score and AlphaFold2.

DAQ-Score

Estimate residue-wise local quality of protein models built from cryo-EM maps.

Secondary Structure Detection

Emap2sec+

Identify protein secondary structures and DNA/RNA in medium-to-low resolution EM maps.

Emap2sec

Identify protein secondary structures in medium-to-low resolution EM maps.

Structure Fitting

VESPER(S2M)

Structure-to-map fitting tool for superimposing models onto EM maps.

VESPER

Map-to-map fitting tool for accurate superimposition of EM maps.

Sequence Search

DAQFinder

Sequence database search using C-alpha backbones traced from EM maps.